Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 6/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936512 | 1.00 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL2453335 | 1.00 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL1792368 | 1.00 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL5670682 | 1.00 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL8607580 | 1.00 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL1258049 | 0.98 | — | — | |
| SCHEMBL405604 | 0.91 | — | — | |
| SCHEMBL29035906 | 0.81 | HDAC2 (0.59) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL28986665 | 0.81 | HDAC2 (0.59) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL27412319 | 0.81 | HDAC2 (0.59) | HDAC2HDAC4HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855545-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | Johnson & Johnson Vision Care Inc. (US) | 2015-04-08 | — | — | EP | claimed |
| WO-2013177506-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | WO | claimed |
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | claimed |
| CN-114907514-A | Multifunctional fiber and preparation method and application thereof | 北京洁尔爽高科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| EP-3843687-A1 | METHODS AND COMPOSITIONS TO STABILIZE A NANOGEL AND DENTAL COMPOSITIONS THEREFROM | DENTSPLY SIRONA Inc. (US) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020047217-A1 | METHODS AND COMPOSITIONS TO STABILIZE A NANOGEL AND DENTAL COMPOSITIONS THEREFROM | DENTSPLY SIRONA INC. (US) | 2020-03-05 | — | — | WO | disclosed |
| EP-2935188-B1 | USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS | DSM IP ASSETS BV (NL) | 2018-08-01 | — | — | EP | disclosed |
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |