Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208831 | 0.77 | TLR4 (0.50) | PARP10SIRT2SLC2A1TLR4TLR2 | |
| SCHEMBL31220919 | 0.77 | TLR4 (0.50) | CETPPARP10SIRT2SLC2A1TLR4 | |
| SCHEMBL4569158 | 0.77 | TLR4 (0.50) | CETPPARP10SIRT2SLC2A1TLR4 | |
| SCHEMBL20946450 | 0.76 | TLR4 (0.48) | PARP10SIRT2SLC2A1TLR4TLR2 | |
| SCHEMBL6890131 | 0.75 | CETP (0.56) | CETPPDK2SIRT2 | |
| SCHEMBL2204659 | 0.75 | CETP (0.49) | CETPPARP10SIRT2SLC2A1TLR4 | |
| SCHEMBL19291583 | 0.75 | CETP (0.49) | CETPPARP10SIRT2SLC2A1TLR4 | |
| SCHEMBL31220912 | 0.75 | TAAR1 (0.51) | PARP10SIRT2SLC2A1TLR4TLR2 | |
| SCHEMBL13881548 | 0.75 | TAAR1 (0.51) | PARP10SIRT2SLC2A1TLR4TLR2 | |
| SCHEMBL8904211 | 0.75 | CYP4F2 (0.55) | CETPPARP10SIRT2SLC2A1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005117869-A1 | COMBINATIONS COMPRISING (S)-AMLODIPINE AND A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR, AND METHODS FOR REDUCING HYPERTENSION | SEPRACOR INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | disclosed |
| EP-1469831-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Pfizer Products Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1401399-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES | Pfizer Products Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003063832-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003000226-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |