Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567282 | 1.00 | MCHR1 (0.66) | MCHR1HTR2C | |
| SCHEMBL567281 | 1.00 | MCHR1 (0.66) | MCHR1HTR2C | |
| SCHEMBL565733 | 0.93 | MCHR1 (0.57) | MCHR1HTR2C | |
| SCHEMBL565732 | 0.93 | MCHR1 (0.57) | MCHR1HTR2C | |
| SCHEMBL565734 | 0.93 | MCHR1 (0.57) | MCHR1HTR2C | |
| SCHEMBL565754 | 0.90 | MCHR1 (0.69) | MCHR1HTR2C | |
| SCHEMBL565755 | 0.90 | MCHR1 (0.69) | MCHR1HTR2C | |
| SCHEMBL927925 | 0.90 | MCHR1 (0.69) | MCHR1HTR2C | |
| SCHEMBL566966 | 0.89 | MCHR1 (0.54) | MCHR1 | |
| SCHEMBL566745 | 0.89 | MCHR1 (0.54) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383647-B2 | Quinoline derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-26 | — | — | US | disclosed |
| US-20120035213-A1 | Quinoline derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2012-02-09 | — | — | US | disclosed |
| EP-2392573-A1 | QUINOLINE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2011-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035213-A1 | Quinoline derivative | MC1R, MCHR1, MCHR2 | MCHR1 2/4885HTR2C 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.