Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672903 | 1.00 | PPARG (0.51) | PPARGPTGDR2APPHDAC1HDAC2 | |
| SCHEMBL5672498 | 0.98 | PPARG (0.47) | PPARGPTGDR2APPHDAC1HDAC2 | |
| SCHEMBL5672499 | 0.98 | PPARG (0.47) | PPARGPTGDR2APPHDAC1HDAC2 | |
| SCHEMBL5674059 | 0.92 | PPARG (0.49) | PPARG | |
| SCHEMBL5674064 | 0.92 | PPARG (0.49) | PPARG | |
| SCHEMBL5672584 | 0.90 | PPARG (0.51) | PPARG | |
| SCHEMBL5672589 | 0.90 | PPARG (0.51) | PPARG | |
| SCHEMBL5672132 | 0.90 | PPARG (0.46) | PPARGPTGDR2APPHDAC1HDAC2 | |
| SCHEMBL5672139 | 0.90 | PPARG (0.46) | PPARGPTGDR2APPHDAC1HDAC2 | |
| SCHEMBL6183211 | 0.89 | PPARG (0.63) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | claimed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |