Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 17/20 | 0.64 |
| ▸ | MC4R | P32245 | 3/20 | 0.63 |
| ▸ | MC3R | P41968 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540734 | 0.95 | PRCP (0.62) | PRCPMC4RMC3R | |
| SCHEMBL91163 | 0.86 | MC4R (0.70) | PRCPMC4RMC3R | |
| SCHEMBL71620 | 0.86 | MC4R (0.70) | PRCPMC4RMC3R | |
| SCHEMBL5227884 | 0.83 | MC4R (0.67) | PRCPMC4RMC3R | |
| SCHEMBL27400473 | 0.83 | MC4R (0.64) | PRCPMC4RMC3R | |
| SCHEMBL27392877 | 0.82 | MC4R (0.73) | PRCPMC4RMC3R | |
| SCHEMBL5617401 | 0.82 | MC4R (0.72) | PRCPMC4RMC3R | |
| SCHEMBL4958465 | 0.82 | MC4R (0.63) | PRCPMC4RMC3R | |
| SCHEMBL5617397 | 0.81 | MC4R (0.67) | PRCPMC4RMC3R | |
| SCHEMBL14540390 | 0.81 | MC4R (0.73) | PRCPMC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483580-A4 | BIOMARKER FOR EFFICACY OF APPETITE SUPPRESSANT DRUGS | MERCK & CO INC (US) | 2006-10-11 | — | — | EP | disclosed |
| EP-1483580-A2 | BIOMARKER FOR EFFICACY OF APPETITE SUPPRESSANT DRUGS | Merck & Co., Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003075742-A2 | BIOMARKER FOR EFFICACY OF APPETITE SUPPRESSANT DRUGS | MERCK & CO., INC. (US) | 2003-09-18 | — | — | WO | disclosed |