Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12570024 | 0.80 | CXCR2 (1.00) | CXCR2 | |
| SCHEMBL6550194 | 0.76 | CXCR2 (0.67) | CXCR2 | |
| SCHEMBL12570031 | 0.74 | CXCR2 (0.76) | CXCR2 | |
| SCHEMBL3881393 | 0.74 | CXCR2 (1.00) | CXCR2 | |
| SCHEMBL12087269 | 0.73 | CXCR2 (0.78) | CXCR2 | |
| SCHEMBL6853270 | 0.73 | CXCR2 (0.77) | CXCR2 | |
| SCHEMBL6549599 | 0.72 | CXCR2 (1.00) | CXCR2 | |
| SCHEMBL12086731 | 0.70 | CXCR2 (0.69) | CXCR2 | |
| SCHEMBL12086750 | 0.70 | CXCR2 (0.72) | CXCR2 | |
| SCHEMBL22198065 | 0.70 | CXCR2 (0.67) | CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357909-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1357909-A1 | IL-8 RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002067919-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-06 | — | — | WO | disclosed |