⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858726 | 0.81 | — | — | |
| SCHEMBL141878 | 0.78 | — | — | |
| SCHEMBL10710350 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL13434035 | 0.77 | GAA (0.42) | — | |
| SCHEMBL28901134 | 0.75 | — | — | |
| SCHEMBL10710353 | 0.75 | — | — | |
| SCHEMBL14962814 | 0.75 | — | — | |
| SCHEMBL8648502 | 0.75 | GAA (0.41) | — | |
| SCHEMBL11672406 | 0.75 | GAA (0.41) | — | |
| SCHEMBL2266278 | 0.75 | GAA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113755088-B | Preparation method of substances required by preparation method of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2022-04-15 | — | — | CN | disclosed |
| WO-2022052936-A1 | ARYL PROPIONIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION, AND METHOD FOR PREPARATION THEREOF AND APPLICATION THEREOF | 南京海融医药科技股份有限公司 | 2022-03-17 | — | — | WO | disclosed |
| CN-113755088-A | Preparation method of substances required by preparation method of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-112646475-B | Preparation and application methods of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112646475-A | Preparation and application methods of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2021-04-13 | — | — | CN | disclosed |
| US-20130131106-A1 | BIFUNCTIONAL RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE | INSPIRE PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2365522-A1 | Electrically isolated power device package | IXYS CORPORATION (US) | 2011-09-14 | — | — | EP | disclosed |
| EP-1534717-B1 | BETA-LACTAMASE INHIBITOR PRODRUG | PFIZER PROD INC (US) | 2006-12-27 | — | — | EP | disclosed |
| US-7091197-B2 | Beta-lactamase inhibitor prodrug | PFIZER INC. (US) | 2006-08-15 | — | — | US | disclosed |
| CN-1688589-A | Beta-lactamase inhibitor prodrug | PFIZER (US) | 2005-10-26 | — | — | CN | disclosed |
| US-20050004093-A1 | Beta-lactamase inhibitor prodrug | PFIZER INC | 2005-01-06 | — | — | US | disclosed |
| US-20040110740-A1 | Beta-lactamase inhibitor prodrug | PFIZER INC | 2004-06-10 | — | — | US | disclosed |
| US-4276285-A | SYNERGISTIC BACTERICIDES | PFIZER INC. (US) | 1981-06-30 | — | — | US | disclosed |
| US-4234579-A | Penicillanic acid 1,1-dioxides as β-lactamase inhibitors | PFIZER INC. (US) | 1980-11-18 | — | — | US | disclosed |