Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675536 | 1.00 | SLC16A3 (0.36) | SLC16A3SLC16A1MCTS1BCL2L1MCL1 | |
| SCHEMBL5675543 | 1.00 | SLC16A3 (0.36) | SLC16A3SLC16A1MCTS1BCL2L1MCL1 | |
| SCHEMBL5672192 | 0.99 | BCL2L1 (0.36) | SLC16A3SLC16A1MCTS1BCL2L1MCL1 | |
| SCHEMBL5672196 | 0.99 | BCL2L1 (0.36) | SLC16A3SLC16A1MCTS1BCL2L1MCL1 | |
| SCHEMBL5672195 | 0.99 | BCL2L1 (0.36) | SLC16A3SLC16A1MCTS1BCL2L1MCL1 | |
| SCHEMBL5672554 | 0.87 | S1PR1 (0.43) | PTGDR2HDAC1APPHDAC2HDAC11 | |
| SCHEMBL5672552 | 0.87 | S1PR1 (0.43) | PTGDR2HDAC1APPHDAC2HDAC11 | |
| SCHEMBL5673937 | 0.87 | HDAC8 (0.39) | MCL1PTGDR2HDAC1APPHDAC2 | |
| SCHEMBL5673941 | 0.87 | HDAC8 (0.39) | MCL1PTGDR2HDAC1APPHDAC2 | |
| SCHEMBL5673036 | 0.86 | PPARG (0.41) | PTGDR2HDAC8PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |