Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 4/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419658 | 1.00 | TDP1 (0.42) | TDP1OPRM1OPRD1CA12CA1 | |
| SCHEMBL29543547 | 0.98 | TDP1 (0.44) | TDP1CA12CA1CA9KDM4E | |
| SCHEMBL15571611 | 0.98 | TDP1 (0.44) | TDP1CA12CA1CA9KDM4E | |
| SCHEMBL30276268 | 0.93 | TDP1 (0.48) | TDP1CA12CA1CA9KDM4E | |
| SCHEMBL4755762 | 0.90 | KDM4E (0.53) | TDP1CA12CA1CA9BACE1 | |
| SCHEMBL29364275 | 0.90 | KDM4E (0.53) | TDP1CA12CA1CA9BACE1 | |
| SCHEMBL1193133 | 0.87 | TDP1 (0.39) | TDP1CA12CA1CA9KDM4E | |
| SCHEMBL30607050 | 0.85 | TDP1 (0.49) | TDP1CA12CA1CA9KDM4E | |
| SCHEMBL29544088 | 0.85 | CA12 (0.49) | TDP1CA12CA1CA9KDM4E | |
| SCHEMBL17312337 | 0.85 | TDP1 (0.49) | TDP1CA12CA1CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611235-A1 | NOVEL ALKALINE PROTEASE | Forskarpatent i Syd AB (SE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004085639-A9 | NOVEL ALKALINE PROTEASE | FORSKARPATENT I SYD AB (SE) | 2005-11-10 | — | — | WO | disclosed |
| WO-2004085639-A1 | NOVEL ALKALINE PROTEASE | FORSKARPATENT I SYD AB (SE) | 2004-10-07 | — | — | WO | disclosed |
| WO-1999022756-A1 | CELL-PERMEABLE PROTEIN INHIBITORS OF CALPAIN | NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. (US) | 1999-05-14 | — | — | WO | disclosed |