SCHEMBL5675601

SCHEMBL5675601

CCCCCOc1ccc(Cn2c(C)nc(Cl)c2C=CC(=O)NS(=O)(=O)CCCCC)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5675597 1.00 PPARG (0.51) PPARG
SCHEMBL5673768 0.98 PPARG (0.49) PPARG
SCHEMBL5673771 0.98 PPARG (0.49) PPARG
SCHEMBL6183218 0.90 PPARG (0.63) PPARG
SCHEMBL6183211 0.90 PPARG (0.63) PPARG
SCHEMBL5213112 0.90 PPARG (0.42) PPARG
SCHEMBL5213109 0.90 PPARG (0.42) PPARG
SCHEMBL5673782 0.89 PPARG (0.47) PPARG
SCHEMBL5673774 0.89 PPARG (0.47) PPARG
SCHEMBL5672601 0.89 PPARG (0.41) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1142879-A1 IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP claimed
US-7060721-B1 Imidazole compounds and medicinal use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2006-06-13 US disclosed
EP-1142879-A1 IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP disclosed