Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.83 |
| ▸ | HTR2B | P41595 | 13/20 | 0.83 |
| ▸ | HTR2A | P28223 | 13/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468401 | 0.91 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL5477497 | 0.91 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL5477541 | 0.91 | HTR2C (0.98) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL5474082 | 0.91 | HTR2C (0.98) | HTR2CHTR2BHTR2A | |
| SCHEMBL5474279 | 0.85 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL5468523 | 0.85 | HTR2C (0.98) | HTR2CHTR2BHTR2A | |
| SCHEMBL5474122 | 0.85 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL5477484 | 0.84 | HTR2C (0.98) | HTR2CHTR2BHTR2A | |
| SCHEMBL5464326 | 0.83 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL5475980 | 0.82 | HTR2C (0.98) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611098-A1 | COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2006-01-04 | — | — | EP | claimed |
| WO-2004089897-A1 | COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2004-10-21 | — | — | WO | claimed |