⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27838627 | 0.96 | — | — | |
| SCHEMBL244401 | 0.96 | — | — | |
| Bicarbonate SCHEMBL2178826 | 0.84 | NAPRT (0.48) | — | |
| SCHEMBL4259192 | 0.82 | HSP90AA1 (0.36) | — | |
| Carbamic Acid SCHEMBL285340 | 0.80 | NAPRT (0.50) | — | |
| SCHEMBL29399188 | 0.65 | — | — | |
| SCHEMBL13217923 | 0.65 | — | — | |
| SCHEMBL21991617 | 0.65 | — | — | |
| SCHEMBL76868 | 0.65 | — | — | |
| SCHEMBL171853 | 0.64 | HDAC8 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 19683 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144793-A1 | METHODS OF TREATING CANCER | AMGEN INC. (US) | 2026-05-28 | — | — | US | claimed |
| EP-4735643-A1 | METHODS FOR EARLY DETECTION OF CANCER | Guardant Health, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| US-20260120878-A1 | METHODS FOR EARLY DETECTION OF CANCER | GUARDANT HEALTH INC (US) | 2026-04-30 | — | — | US | claimed |
| EP-4716553-A1 | METHODS OF TREATMENT USING ANTI-C-MET ANTIBODY DRUG CONJUGATES | AbbVie Manufacturing Management Unlimited Company (IE) | 2026-04-01 | — | — | EP | claimed |
| US-12553903-B2 | Ivaltinostat combination therapy for treating pancreatic cancer | CG PHARMACEUTICALS, INC (US) | 2026-02-17 | — | — | US | claimed |
| US-20260034212-A1 | METHODS OF TREATING TUMORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-02-05 | — | — | US | claimed |
| US-20260021106-A1 | COMBINATION THERAPY FOR TREATING CANCERS | GEISTLICH PHARMA AG (CH) | 2026-01-22 | — | — | US | claimed |
| US-12527838-B2 | Combination therapies comprising an agent that blocks the interaction between CD47 and SIRPα for treating gastric or gastroesphageal junction cancel | ALX Oncology Inc. (US) | 2026-01-20 | — | — | US | claimed |
| US-20250376536-A1 | MULTISPECIFIC ANTI-CD40 / ANTI-FAP ANTIBODIES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-12-11 | — | — | US | claimed |
| US-20250368712-A1 | METHODS OF TREATING CANCER | ALX ONCOLOGY INC (US) | 2025-12-04 | — | — | US | claimed |
| EP-0123907-B1 | FLUOROPYRIMIDINE DERIVATIVES | Chisso Corporation (JP) | 1989-07-26 | — | — | EP | claimed |
| EP-0203505-B1 | DISAZO METAL COMPLEX DYES | BAYER AG (DE) | 1989-05-24 | — | — | EP | claimed |
| EP-0290144-A1 | Method of detecting incipient resistance to therapeutic agents in cancer patients | City of Hope (US) | 1988-11-09 | — | — | EP | claimed |
| EP-0203505-A1 | Disazo metal complex dyes | BAYER AG (DE) | 1986-12-03 | — | — | EP | claimed |
| EP-0097289-B1 | AZO DYESTUFFS | BAYER AG (DE) | 1986-10-15 | — | — | EP | claimed |
| EP-0041922-B1 | PROCESS FOR THE PREPARATION OF AMINO-SUBSTITUTED 1-AMINO-8-HYDROXY-NAPHTHALENE-SULFONIC ACIDS | CIBA-GEIGY AG (CH) | 1984-10-03 | — | — | EP | claimed |
| EP-0043927-B1 | PROCESS FOR PREPARING REACTIVE AZO DYESTUFFS | BAYER AG (DE) | 1984-05-16 | — | — | EP | claimed |
| EP-0097289-A2 | Azo dyestuffs | BAYER AG (DE) | 1984-01-04 | — | — | EP | claimed |
| EP-0017172-B1 | PROCESS FOR DYEING CELLULOSE FIBRES, AND FIBRE BLENDS THAT CONTAIN CELLULOSE/POLYESTER FIBRES, WITH REACTIVE DYES | BAYER AG (DE) | 1982-08-25 | — | — | EP | claimed |
| US-4024143-A | Silylation of 5-fluoro-6-hydroxy or alkoxy pyrimidine | PCR, INC. (US) | 1977-05-17 | — | — | US | claimed |