Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 5/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677285 | 0.81 | HDAC1 (0.43) | HDAC1HPGDCLK1LMNAL3MBTL1 | |
| SCHEMBL5896917 | 0.80 | HRH3 (0.41) | HPGDKMT2ALMNAL3MBTL1 | |
| SCHEMBL2789271 | 0.73 | AKT1 (0.44) | AKT1 | |
| SCHEMBL30192993 | 0.71 | HDAC1 (0.39) | HDAC1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL23833190 | 0.71 | HDAC1 (0.39) | HDAC1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL27015387 | 0.71 | HDAC1 (0.40) | HDAC1KMT2ACLK1DYRK1ACLK2 | |
| SCHEMBL23833149 | 0.71 | HDAC1 (0.40) | HDAC1KMT2ACLK1DYRK1ACLK2 | |
| SCHEMBL5896966 | 0.68 | HRH3 (0.46) | AKT1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL5896915 | 0.68 | HRH3 (0.57) | HPGDKMT2ALMNAL3MBTL1 | |
| SCHEMBL1887657 | 0.67 | HDAC1 (0.55) | HDAC1HPGDKMT2ACLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| EP-1556035-A4 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECH INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1556035-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026264-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | AKT1 2563/4885HDAC1 227/4885CYP1A2 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.