SCHEMBL5677387

SCHEMBL5677387

FC1(Cl)C(Cl)=C(Cl)C(F)(Cl)C1(F)Cl

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9470491 0.84 MEN1 (0.38) MEN1THRBRECQLKMT2AALDH1A1
SCHEMBL5677095 0.83
SCHEMBL5676822 0.83
SCHEMBL5677148 0.81
SCHEMBL4830348 0.77 MEN1 (0.33) MEN1THRBRECQLKMT2AALDH1A1
SCHEMBL9328074 0.74 MEN1 (0.32) MEN1THRBRECQLKMT2AALDH1A1
SCHEMBL9471163 0.72 MEN1 (0.30) MEN1THRBRECQLKMT2AALDH1A1
SCHEMBL2811137 0.70
SCHEMBL5679107 0.69
SCHEMBL4830258 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1017656-B1 METHOD FOR PRODUCING PERHALOGENATED CYCLOPENTENE CENTRAL GLASS CO LTD (JP) 2005-04-06 EP claimed
CN-110637001-B Process for producing octafluorocyclopentene 日本瑞翁株式会社 2022-05-27 CN disclosed
CN-110650937-B Process for producing octafluorocyclopentene 日本瑞翁株式会社 2022-04-05 CN disclosed
US-10717690-B2 Method of manufacturing octafluorocyclopentene ZEON CORPORATION (JP) 2020-07-21 US disclosed
US-10710946-B2 Method of manufacturing octafluorocyclopentene ZEON CORPORATION (JP) 2020-07-14 US disclosed
US-20200199050-A1 METHOD OF MANUFACTURING OCTAFLUOROCYCLOPENTENE ZEON CORPORATION (JP) 2020-06-25 US disclosed
US-20200181046-A1 METHOD OF MANUFACTURING OCTAFLUOROCYCLOPENTENE ZEON CORPORATION (JP) 2020-06-11 US disclosed
CN-110650937-A Process for producing octafluorocyclopentene 日本瑞翁株式会社 2020-01-03 CN disclosed
CN-110637001-A Process for producing octafluorocyclopentene 日本瑞翁株式会社 2019-12-31 CN disclosed
EP-0999195-B1 Method for preparing perhalogenated five-membered cyclic compound CENTRAL GLASS CO LTD (JP) 2006-02-08 EP disclosed
EP-1017656-B1 METHOD FOR PRODUCING PERHALOGENATED CYCLOPENTENE CENTRAL GLASS CO LTD (JP) 2005-04-06 EP disclosed
US-6395940-B1 CATALYTIC FLUORINATION OF OCTACHLOROCYCLOPENTENE CENTRAL GLASS COMPANY, LIMITED (JP) 2002-05-28 US disclosed
US-6218586-B1 FLUORINATION OF PERHALOGENATED CYCLOPENTENE TO PERHALOGENATED CYCLOPENTANE USING FLUORINE AND HYDROGEN CHLORIDE IN PRESENCE OF METAL COMPOUND CATALYST ON ACTIVE CARBON SUPPORT; SATURATION CENTRAL GLASS COMPANY, LIMITED (JP) 2001-04-17 US disclosed
EP-1017656-A1 METHOD FOR PRODUCING PERHALOGENATED CYCLOPENTENE Central Glass Company, Limited (JP) 2000-07-12 EP disclosed
EP-0999195-A1 Method for preparing perhalogenated five-membered cyclic compound Central Glass Company, Limited (JP) 2000-05-10 EP disclosed
WO-1999014173-A1 METHOD FOR PRODUCING PERHALOGENATED CYCLOPENTENE CENTRAL GLASS COMPANY, LIMITED (JP) 1999-03-25 WO disclosed
US-5233105-A Fluorination using hydrogen fluoride BAYER AKTIENGESELLSCHAFT (DE) 1993-08-03 US disclosed
US-5180861-A PROCESS FOR THE PREPARATION OF POLYCHLORO-FLUORO-CYCLO-PENTENES BAYER AKTIENGESELLSCHAFT (DE) 1993-01-19 US disclosed