Isothiazole

Isothiazole

SCHEMBL5679

c1cnsc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isothiazole SCHEMBL642842 1.00
Isothiazole SCHEMBL27729992 0.96
Isothiazole SCHEMBL28200799 0.96
Benzene SCHEMBL27379971 0.96
Isothiazole SCHEMBL28981301 0.96
Isothiazole SCHEMBL28063961 0.96
Isothiazole SCHEMBL9391996 0.96
Isothiazole SCHEMBL30450994 0.96
Isothiazole SCHEMBL28168124 0.96
Isothiazole SCHEMBL27525564 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 111146 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146050-A1 KRAS DEGRADING COMPOUNDS COMPRISING SPIROCYCLIC ANNULATED 2 AMINO-3-CYANO THIOPHENES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-05-28 US claimed
US-20260146049-A1 SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-05-28 US claimed
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS DONG-A ST CO., LTD. (KR) 2026-05-28 US claimed
CN-122080076-A Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device 2026-05-26 CN claimed
CN-122071475-A Ternary condensed ring derivative and medical application thereof 杭州百新生物医药科技有限公司 2026-05-22 CN claimed
WO-2026106499-A1 OREXIN RECEPTOR ANTAGONISTS: 2-AZABICYCLIC COMPOUNDS BIAL - PORTELA & CA., S.A. (PT) 2026-05-21 WO claimed
US-20260137650-A1 MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) 11949098 CANADA INC (CA) 2026-05-21 US claimed
US-20260137666-A1 N-methyl-D-aspartic Acid Receptor Modulators EMORY UNIV (US) 2026-05-21 US claimed
EP-4743120-A1 MOLECULAR DEGRADERS FOR THE TREATMENT OF IGA NEPHROPATHY Biohaven Therapeutics Ltd. (VG) 2026-05-20 EP claimed
EP-4105216-B1 DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF GENFLEET THERAPEUTICS SHANGHAI INC (CN) 2026-05-20 EP claimed
US-4085098-A Azo dyes containing a heterocyclic ring having a quaternized nitrogen atom and at least one optionally substituted phenoxyalkyl or naphthyloxyalkyl substituent SANDOZ LTD. (CH) 1978-04-18 US claimed
US-4080327-A 13-Oxatetracyclo[8.2.12,9.0.03,8 ]tridec-5-ene-1,5,6,10-tetracarbonitrile and separation of its monocyclic aromatic clathrates PHILLIPS PETROLEUM COMPANY (US) 1978-03-21 US claimed
US-4080459-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1978-03-21 US claimed
US-4070475-A THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1978-01-24 US claimed
US-4057416-A 3-Alkylthio-, 3-alkylsulfinyl-, and 3-alkylsulfonylisothiazole derivatives as herbicides FMC CORPORATION (US) 1977-11-08 US claimed
US-4039541-A Monocyclic aromatic clathrates of 13-oxatetracyclo[8.2.12,9.0.03,8 ]tridec-5-ene-1,5,6,10-tetracarbonitrile PHILLIPS PETROLEUM COMPANY (US) 1977-08-02 US claimed
US-4028323-A WITH A SUBSTITUTED AMINOBENZENE CIBA-GEIGY AG (CH) 1977-06-07 US claimed
US-4022797-A PHARMACEUTICALS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-05-10 US claimed
US-4014864-A POLYESTER FIBERS CIBA-GEIGY CORPORATION (US) 1977-03-29 US claimed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US claimed