Dextrose

Dextrose

SCHEMBL5679244

O=c1ccc2nc3ccccc3oc-2c1.OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 3/20 0.49
APP P05067 12/20 0.48
CYP1A2 P05177 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
ALPL P05186 1/20 0.43
POLB P06746 1/20 0.43
ALPI P09923 1/20 0.43
MAPT P10636 1/20 0.43
ALPG P10696 1/20 0.43
RECQL P46063 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-D-Glucose SCHEMBL383291 1.00 SLC5A2 (0.49) SLC5A2APPCYP1A2KDM4EMEN1
B-D-Galactose SCHEMBL8515088 1.00 SLC5A2 (0.49) SLC5A2APPCYP1A2KDM4EMEN1
D-Galactose SCHEMBL2370315 1.00 SLC5A2 (0.49) SLC5A2APPCYP1A2KDM4EMEN1
B-D-Galactose SCHEMBL1712843 1.00 SLC5A2 (0.49) SLC5A2APPCYP1A2KDM4EMEN1
B-D-Galactose SCHEMBL307802 1.00 SLC5A2 (0.49) SLC5A2APPCYP1A2KDM4EMEN1
Beta-D-Glucose SCHEMBL3018938 0.87 APP (0.68) APPCYP1A2KDM4EMEN1ALDH1A1
D-Galactose SCHEMBL15391861 0.87 APP (0.68) APPCYP1A2KDM4EMEN1ALDH1A1
B-D-Galactose SCHEMBL307801 0.87 APP (0.68) APPCYP1A2KDM4EMEN1ALDH1A1
N-Acetylglucosamine SCHEMBL5692330 0.86 HK1 (0.43) SLC5A2APPCYP1A2POLB
SCHEMBL3827094 0.85 APP (0.49) SLC5A2APPCYP1A2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1616032-A2 DETECTING GENE EXPRESSION IN LIVE CELLS USING SHORT-LIVED REPORTERS WITH ENZYMATIC AMPLIFICATION President And Fellows of Harvard College (US) 2006-01-18 EP claimed
WO-2004090104-A2 DETECTING GENE EXPRESSION IN LIVE CELLS USING SHORT-LIVED REPORTERS WITH ENZYMATIC AMPLIFICATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2004-10-21 WO claimed
EP-3183362-A1 ELECTROCHEMICAL DETECTION OF MICROORGANISMS Nanyang Technological University (SG) 2017-06-28 EP disclosed
EP-2864048-B1 MICROFLUIDIC DEVICE FOR DROPLET GENERATION IMP INNOVATIONS LTD (GB) 2016-11-09 EP disclosed
WO-2016028233-A1 ELECTROCHEMICAL DETECTION OF MICROORGANISMS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-02-25 WO disclosed
US-20150174576-A1 Microfluidic Device for Droplet Generation CAMBRIDGE ENTERPRISE LIMITED (GB) 2015-06-25 US disclosed
EP-2864048-A1 MICROFLUIDIC DEVICE FOR DROPLET GENERATION Imperial Innovations Limited (GB) 2015-04-29 EP disclosed
WO-2014001781-A1 MICROFLUIDIC DEVICE FOR DROPLET GENERATION IMPERIAL INNOVATIONS LIMITED (GB) 2014-01-03 WO disclosed
EP-1616032-A2 DETECTING GENE EXPRESSION IN LIVE CELLS USING SHORT-LIVED REPORTERS WITH ENZYMATIC AMPLIFICATION President And Fellows of Harvard College (US) 2006-01-18 EP disclosed
WO-2004090104-A2 DETECTING GENE EXPRESSION IN LIVE CELLS USING SHORT-LIVED REPORTERS WITH ENZYMATIC AMPLIFICATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2004-10-21 WO disclosed
EP-0156347-B1 GLYCOSIDES OF RESOFURIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE IN THE DETERMINATION OF THE ACTIVITY OF GLYCOSIDASES Roche Diagnostics GmbH (DE) 1991-09-04 EP disclosed
EP-0156347-A2 Glycosides of resofurin derivatives, method for their preparation and their use in the determination of the activity of glycosidases Roche Diagnostics GmbH (DE) 1985-10-02 EP disclosed