Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.80 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28261860 | 0.95 | CA1 (0.73) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL51 | 0.95 | — | — | |
| Acetic Acid SCHEMBL5082363 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL10578328 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL711373 | 0.91 | CA1 (0.67) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL28237750 | 0.91 | CA1 (0.67) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL25229790 | 0.90 | — | — | |
| Acetic Acid SCHEMBL9718803 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL11586801 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL8853012 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998523-B1 | COMPOSITION CONTAINING AMPHIIONIC RESIN AND POLYVALENT METAL COMPLEX | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-08-25 | — | — | EP | claimed |
| EP-0998523-A1 | COMPOSITION CONTAINING AMPHIIONIC RESIN AND POLYVALENT METAL COMPLEX | THE DOW CHEMICAL COMPANY (US) | 2000-05-10 | — | — | EP | claimed |
| US-5959016-A | POLYMER WITH PENDANT CATIONIC GROUPS AND WEAK SALT GROUPS AND SOLVENT WITH POLYVALENT METAL COMPLEXES TACK-FREE, SOLVENT-RESISTANT COATING. | THE DOW CHEMICAL COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| WO-1999006478-A1 | COMPOSITION CONTAINING AMPHIIONIC RESIN AND POLYVALENT METAL COMPLEX | THE DOW CHEMICAL COMPANY (US) | 1999-02-11 | — | — | WO | claimed |
| CN-116920589-A | H in plastic waste gas 2 S-based absorbent and absorbent system | 广东凯凌生态环境科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116259751-A | Electrode protection material and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-06-13 | — | — | CN | disclosed |
| CN-112844358-A | Preparation method of graphene zinc oxide nanocomposite | 常州恒利宝纳米新材料科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-107817314-A | A kind of quick judgement sodium chromate adds the method for sulphur reduction reaction terminal | 中信锦州金属股份有限公司 | 2018-03-20 | — | — | CN | disclosed |
| EP-1525280-B1 | AQUEOUS RESIN DISPERSION FOR FLOORS, AND FLOOR POLISH USING SAME | JOHNSON DIVERSEY INC (US) | 2006-03-01 | — | — | EP | disclosed |
| US-20050222322-A1 | Aqueous resin dispersion for floors, and floor polish using same | JOHNSONDIVERSEY, INC. | 2005-10-06 | — | — | US | disclosed |
| CN-1671813-A | Aqueous resin dispersion for floors, and floor polish using same | JOHNSON DIVERSEY INC (US) | 2005-09-21 | — | — | CN | disclosed |
| EP-1525280-A1 | AQUEOUS RESIN DISPERSION FOR FLOORS, AND FLOOR POLISH USING SAME | JohnsonDiversey, Inc. (US) | 2005-04-27 | — | — | EP | disclosed |
| CN-1217316-A | Preparation for unsaturated ketone | BASF AG (DE) | 1999-05-26 | — | — | CN | disclosed |
| WO-1999006478-A1 | COMPOSITION CONTAINING AMPHIIONIC RESIN AND POLYVALENT METAL COMPLEX | THE DOW CHEMICAL COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0511681-B1 | Gloves and methods of manufacturing the same | SUMITOMO RUBBER IND (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5459880-A | Laminate of natural rubber and acrylonitrile-butadiene copolymer | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5326515-A | Immersion of glove mold in natural rubber latex then immersion part of mold in different rubber latex and drying to laminate | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0511681-A1 | Gloves and methods of manufacturing the same | SUMITOMO RUBBER INDUSTRIES LIMITED (JP) | 1992-11-04 | — | — | EP | disclosed |
| EP-0228481-A1 | Coating composition | YUHO CHEMICALS INC. (JP) | 1987-07-15 | — | — | EP | disclosed |
| US-4622360-A | FLOORS, POLYURETHANE CONTAINING CARBOXYLATE GROUPS CROSSLINKED WITH METAL | YUHO CHEMICALS INC. (JP) | 1986-11-11 | — | — | US | disclosed |