Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5679014 | 0.98 | ANPEP (0.55) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL5681075 | 0.98 | S1PR2 (0.58) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL7617519 | 0.98 | ANPEP (0.55) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5680818 | 0.98 | ANPEP (0.55) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL5681630 | 0.98 | S1PR2 (0.58) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5683006 | 0.96 | S1PR2 (0.56) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5681163 | 0.96 | S1PR2 (0.56) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL7622011 | 0.96 | S1PR2 (0.56) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5681170 | 0.96 | S1PR2 (0.56) | ANPEPS1PR2S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL7620762 | 0.96 | S1PR2 (0.56) | ANPEPS1PR2S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | claimed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | claimed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | claimed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | claimed |
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | disclosed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | disclosed |