Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5676545 | 0.98 | CHAT (0.45) | CHATKMT2ARXFP1RAD52RAB9A | |
| Iodide SCHEMBL6847802 | 0.98 | CHAT (0.45) | CHATKMT2ARXFP1RAD52RAB9A | |
| SCHEMBL13989158 | 0.85 | KMT2A (0.49) | KMT2ARXFP1RAD52ALDH1A1KDM4E | |
| SCHEMBL13989159 | 0.83 | KMT2A (0.53) | KMT2ARXFP1RAD52ALDH1A1KDM4E | |
| SCHEMBL18102250 | 0.81 | KDM4A (0.42) | CHATKMT2ARXFP1RAD52RAB9A | |
| SCHEMBL14392935 | 0.80 | KMT2A (0.40) | KMT2ARXFP1RAD52ALDH1A1KDM4E | |
| SCHEMBL13428293 | 0.79 | KMT2A (0.39) | KMT2ARXFP1RAD52RAB9AALDH1A1 | |
| SCHEMBL10104165 | 0.79 | KMT2A (0.39) | KMT2ARXFP1RAD52ALDH1A1KDM4E | |
| SCHEMBL16070432 | 0.78 | CHKA (0.43) | KMT2ARXFP1RAD52RAB9AALDH1A1 | |
| SCHEMBL18159321 | 0.78 | KMT2A (0.45) | KMT2ARXFP1RAD52RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| US-10024863-B2 | Methods for dye selection for protein melt temperature determinations | Life Technologies Corporation (US) | 2018-07-17 | — | — | US | disclosed |
| US-20140315190-A1 | METHODS FOR DYE SELECTION FOR PROTEIN MELT TEMPERATURE DETERMINATIONS | Life Technologies Corporation | 2014-10-23 | — | — | US | disclosed |