Methacrylic Acid

Methacrylic Acid

SCHEMBL5680779

C1CO1.C1CO1.C1CO1.C1CO1.C=C(C)C(=O)O.C=C(C)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FFAR3 O14843 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 2/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5680494 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL51588 1.00
Methacrylic Acid SCHEMBL2955218 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL5491852 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL2951300 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL2592759 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL5445775 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL2948016 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL7152497 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN
Methacrylic Acid SCHEMBL2129792 1.00 SMN1; SMN2 (0.40) SMN1; SMN2TDP1FFAR3LCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1634562-A1 Dental filler particles and method for their preparation and use DENTSPLY DETREY GmbH (DE) 2006-03-15 EP claimed
JP-57026748-A None JP disclosed
EP-1634562-A1 Dental filler particles and method for their preparation and use DENTSPLY DETREY GmbH (DE) 2006-03-15 EP disclosed
US-5480946-A CONTACT LENSES CIBA GEIGY CORPORATION (US) 1996-01-02 US disclosed
EP-0291452-B1 Terminal polyvinyl functional macromers, polymers thereof and contact lenses made therefrom CIBA GEIGY AG (CH) 1994-06-01 EP disclosed
EP-0455585-B1 Unsaturated urea polysiloxanes CIBA GEIGY AG (CH) 1994-03-23 EP disclosed
EP-0455585-A1 Unsaturated urea polysiloxanes CIBA-GEIGY AG (CH) 1991-11-06 EP disclosed
US-4837289-A CONTACT LENSES CIBA-GEIGY CORPORATION (US) 1989-06-06 US disclosed
EP-0291452-A2 Terminal polyvinyl functional macromers, polymers thereof and contact lenses made therefrom CIBA-GEIGY AG (CH) 1988-11-17 EP disclosed
JP-S5726748-A METHOD FOR SEPARATING AND PURIFYING WATER-SOLUBLE SUBSTANCE SEKISUI CHEM CO LTD 1982-02-12 JP disclosed