Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767389 | 1.00 | AR (0.64) | ARALDH1A1HPGDKMT2APOLB | |
| SCHEMBL12591156 | 0.92 | AR (0.65) | AR | |
| SCHEMBL2769146 | 0.92 | AR (0.65) | AR | |
| SCHEMBL2767185 | 0.91 | AR (0.64) | AR | |
| SCHEMBL18671312 | 0.91 | AR (0.64) | AR | |
| SCHEMBL2768630 | 0.90 | AR (0.76) | AR | |
| SCHEMBL2767427 | 0.90 | AR (0.78) | AR | |
| SCHEMBL2767876 | 0.90 | AR (0.63) | AR | |
| SCHEMBL2767724 | 0.90 | AR (0.63) | AR | |
| SCHEMBL12706728 | 0.90 | AR (0.63) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641745-A1 | PROPIONAMIDE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | Orion Corporation (FI) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000794-A1 | PROPIONAMIDE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | ORION CORPORATION (FI) | 2005-01-06 | — | — | WO | disclosed |