SCHEMBL5683003

SCHEMBL5683003

Nc1nccc(Cl)c1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1056076 0.75
SCHEMBL5349778 0.75
SCHEMBL27663241 0.75
SCHEMBL31094386 0.75
SCHEMBL2360937 0.75
SCHEMBL6130237 0.75
SCHEMBL559525 0.75
SCHEMBL29479544 0.75
SCHEMBL23508892 0.71
SCHEMBL2590367 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104224781-B The pyridine compounds and their and its new application of one group of 2- amide groups -3- alkoxy substitution 中国医学科学院医药生物技术研究所 2018-09-25 CN disclosed
CN-104224781-A 2-acylamino-3-alkoxyl substituted pyridine compounds and novel use thereof INST MED BIOTECHNOLOGY CAMS 2014-12-24 CN disclosed
US-20100160346-A1 NEUROLOGICALLY ACTIVE COMPOUNDS PRANA BIOTECHNOLOGY LIMITED (AU) 2010-06-24 US disclosed
US-20100160346-A1 NEUROLOGICALLY ACTIVE COMPOUNDS PRANA BIOTECHNOLOGY LIMITED (AU) 2010-06-24 US disclosed
US-7692011-B2 8-hydroxy and 8-mercapto quinazolinones PRANA BIOTECHNOLOGY LIMITED (AU) 2010-04-06 US disclosed
US-7692011-B2 8-hydroxy and 8-mercapto quinazolinones PRANA BIOTECHNOLOGY LIMITED (AU) 2010-04-06 US disclosed
EP-1534227-B1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KGAA (DE) 2006-12-27 EP disclosed
EP-1272150-B1 COLORING AGENTS CONTAINING RUTHENIUM COMPOUNDS HENKEL KGAA (DE) 2006-03-01 EP disclosed
US-4022897-A 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES E. R. SQUIBB & SONS, INC. (US) 1977-05-10 US disclosed