Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757387 | 0.80 | TDP1 (0.42) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL4494055 | 0.78 | MEN1 (0.40) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL3919530 | 0.78 | MEN1 (0.50) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL16757280 | 0.78 | TDP1 (0.46) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL5683230 | 0.78 | TDP1 (0.41) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL16757335 | 0.76 | SLC6A2 (0.41) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL21910180 | 0.74 | CYP2D6 (0.51) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL21910174 | 0.74 | CYP2D6 (0.51) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL4492193 | 0.74 | TDP1 (0.41) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL28960292 | 0.73 | MEN1 (0.43) | OPRD1CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060258684-A1 | 2-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl]ethoxy]acetic acid monohydrochloride as anti-allergenic compound and process for its production | WOCKHARDT LIMITED (IN) | 2006-11-16 | — | — | US | disclosed |
| EP-1628964-A1 | 2-[2-[4-[(4-CHLOROPHENYL) PHENYLMETHYL] -1-PIPERAZINYL] ETHOXY] ACETIC ACID MONOHYDROCHLORIDE AS ANTI-ALLERGENIC COMPOUND AND PROCESS FOR ITS PRODUCTION | Wockhardt Limited (IN) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004103982-A1 | 2-[2-[4-[(4-CHLOROPHENYL) PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]ACETIC ACID MONOHYDROCHLORIDE AS ANTI-ALLERGENIC COMPOUND AND PROCESS FOR ITS PRODUCTION | WOCKHARDT LIMITED (US) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258684-A1 | 2-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl]ethoxy]acetic acid monohydrochloride as anti-allergenic compound and process for its production | CMA1, HRH2, HRH1 | OPRM1 2829/4885OPRD1 2663/4885OPRK1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.