Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809167 | 0.81 | CSNK2A1 (0.39) | CSNK2A1TYMSALDH1A1LMNAHPGD | |
| SCHEMBL5681013 | 0.80 | FABP6 (0.50) | FABP6CSNK2A2CSNK2BCSNK2A1TYMS | |
| SCHEMBL1192890 | 0.78 | GRIN2D (0.31) | ALDH1A1 | |
| SCHEMBL6626586 | 0.77 | FABP6 (0.55) | FABP6TYMSALDH1A1PLAUHTR3E | |
| SCHEMBL16936702 | 0.74 | TYMS (0.40) | FABP6CSNK2A2CSNK2BCSNK2A1TYMS | |
| SCHEMBL6517964 | 0.73 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2541923 | 0.69 | FABP6 (0.46) | FABP6TYMSALDH1A1PLAUHTR3E | |
| SCHEMBL5924316 | 0.69 | FABP6 (0.50) | FABP6TYMSALDH1A1PLAUHTR3E | |
| SCHEMBL6621861 | 0.69 | FABP6 (0.50) | FABP6TYMSALDH1A1PLAUHTR3E | |
| SCHEMBL23295593 | 0.68 | FABP6 (0.59) | FABP6TYMSALDH1A1PLAUHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |