Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683612 | 1.00 | MEN1 (0.43) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6459410 | 0.93 | CYP2C9 (0.44) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6459404 | 0.93 | CYP2C9 (0.44) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6454896 | 0.89 | CYP2C9 (0.42) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6454892 | 0.89 | CYP2C9 (0.42) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL5683851 | 0.87 | MEN1 (0.44) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL12032226 | 0.87 | CYP2C9 (0.48) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL12032005 | 0.87 | CYP2C9 (0.48) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL12031929 | 0.87 | CYP2C9 (0.49) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL5683761 | 0.86 | MEN1 (0.35) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |