Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.38 |
| ▸ | SGPL1 | O95470 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684036 | 1.00 | S1PR1 (0.38) | S1PR1SGPL1CYP3A4CYP2C8S1PR3 | |
| SCHEMBL5684046 | 1.00 | S1PR1 (0.38) | S1PR1SGPL1CYP3A4CYP2C8S1PR3 | |
| SCHEMBL5684050 | 1.00 | S1PR1 (0.38) | S1PR1SGPL1CYP3A4CYP2C8S1PR3 | |
| SCHEMBL5686557 | 0.90 | S1PR1 (0.37) | S1PR1SGPL1 | |
| SCHEMBL5686541 | 0.90 | S1PR1 (0.37) | S1PR1SGPL1 | |
| SCHEMBL5686545 | 0.90 | S1PR1 (0.37) | S1PR1SGPL1 | |
| SCHEMBL5686553 | 0.90 | S1PR1 (0.37) | S1PR1SGPL1 | |
| SCHEMBL5684548 | 0.90 | S1PR1 (0.35) | S1PR1SGPL1 | |
| SCHEMBL5684553 | 0.90 | S1PR1 (0.35) | S1PR1SGPL1 | |
| SCHEMBL5684560 | 0.90 | S1PR1 (0.35) | S1PR1SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |