Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684222 | 1.00 | MEN1 (0.32) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6452555 | 0.94 | CYP2C9 (0.33) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6452549 | 0.94 | CYP2C9 (0.33) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6451224 | 0.90 | TLR4 (0.34) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6451220 | 0.90 | TLR4 (0.34) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL12028507 | 0.87 | CYP2C9 (0.38) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL14526193 | 0.86 | MEN1 (0.31) | MEN1KMT2AMAPT | |
| SCHEMBL5684456 | 0.86 | — | — | |
| SCHEMBL5684451 | 0.86 | — | — | |
| SCHEMBL5687520 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |