Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684671 | 1.00 | PPARA (0.37) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5885067 | 0.94 | PPARD (0.38) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5885070 | 0.94 | PPARD (0.38) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5684862 | 0.93 | PPARD (0.38) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5684859 | 0.93 | PPARD (0.38) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5687235 | 0.93 | PPARD (0.37) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5687231 | 0.93 | PPARD (0.37) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5683415 | 0.93 | PPARD (0.37) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5683410 | 0.93 | PPARD (0.37) | PPARAPPARDAKR1C3FFAR1PPIB | |
| SCHEMBL5687260 | 0.92 | PPARA (0.38) | PPARAPPARDAKR1C3FFAR1PPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |