Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | PPM1A | P35813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3162399 | 0.95 | GRM2 (0.37) | GRM2CHRNA7TSHRGSK3BNCEH1 | |
| SCHEMBL3170923 | 0.94 | GSK3B (0.37) | GRM2CHRNA7TSHRGSK3BNCEH1 | |
| SCHEMBL3153576 | 0.93 | DAO (0.37) | GRM2CHRNA7TSHRGSK3BNCEH1 | |
| SCHEMBL3160311 | 0.90 | ALOX5AP (0.41) | GRM2CHRNA7TSHRGSK3BNCEH1 | |
| SCHEMBL6059636 | 0.88 | GSK3B (0.39) | GRM2CHRNA7TSHRGSK3BFFAR4 | |
| SCHEMBL3168398 | 0.88 | MPL (0.41) | GRM2TSHRGSK3BFFAR4MPL | |
| SCHEMBL3158555 | 0.87 | MPL (0.40) | GRM2TSHRGSK3BMPLPPARA | |
| SCHEMBL3172144 | 0.87 | RARB (0.39) | GRM2MPL | |
| SCHEMBL3169965 | 0.87 | DAO (0.38) | GRM2TSHRGSK3BFFAR4MPL | |
| SCHEMBL6059671 | 0.87 | PTGDR2 (0.35) | GRM2CHRNA7TSHRGSK3BNCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |