Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685153 | 1.00 | NPC1 (0.53) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| SCHEMBL27744415 | 0.85 | NPC1 (0.47) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| Itaconate SCHEMBL28357783 | 0.82 | NPC1 (0.45) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| SCHEMBL27668209 | 0.79 | NPC1 (0.53) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| SCHEMBL11341834 | 0.79 | NPC1 (0.53) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| SCHEMBL2033350 | 0.79 | NPC1 (0.63) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| SCHEMBL11341830 | 0.79 | NPC1 (0.53) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| SCHEMBL4960106 | 0.78 | F2 (0.41) | KMT2APLGPLAUPLATKLK1 | |
| Hydrochloric Acid SCHEMBL27781046 | 0.78 | NPC1 (0.61) | NPC1RAB9AHDAC1HDAC2HDAC6 | |
| SCHEMBL11333077 | 0.78 | NPC1 (0.61) | NPC1RAB9AHDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018159-A1 | ION EXCHANGE RESINS | MONTECH PTY. LTD. (AU) | 1995-07-06 | — | — | WO | claimed |
| EP-1112389-B1 | PROCESS FOR RECOVERY OF GOLD AND/OR SILVER | ORETEK LTD (AU) | 2006-03-15 | — | — | EP | disclosed |
| EP-1112389-A4 | PROCESS FOR RECOVERY OF GOLD AND/OR SILVER | ORETEK LTD (AU) | 2004-05-06 | — | — | EP | disclosed |
| EP-1112389-A1 | PROCESS FOR RECOVERY OF GOLD AND/OR SILVER | Arton (No. 001) Pty. Ltd. (AU) | 2001-07-04 | — | — | EP | disclosed |
| WO-1999013116-A1 | PROCESS FOR RECOVERY OF GOLD AND/OR SILVER | ARTON (NO. 001) PTY. LTD. (AU) | 1999-03-18 | — | — | WO | disclosed |
| WO-1995018159-A1 | ION EXCHANGE RESINS | MONTECH PTY. LTD. (AU) | 1995-07-06 | — | — | WO | disclosed |