Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12707473 | 1.00 | AR (0.58) | ARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2766530 | 1.00 | AR (0.58) | ARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2767366 | 0.94 | AR (0.58) | ARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2765748 | 0.91 | AR (0.60) | ARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12707432 | 0.91 | AR (0.61) | ARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12707469 | 0.91 | AR (0.60) | ARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12706728 | 0.90 | AR (0.63) | AR | |
| SCHEMBL2767876 | 0.90 | AR (0.63) | AR | |
| SCHEMBL2766992 | 0.89 | AR (0.58) | ARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2767715 | 0.88 | AR (0.57) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641745-A1 | PROPIONAMIDE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | Orion Corporation (FI) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000794-A1 | PROPIONAMIDE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | ORION CORPORATION (FI) | 2005-01-06 | — | — | WO | disclosed |