Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701978 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5685648 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL7064462 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5685799 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5688789 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5685795 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL8017580 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5685802 | 1.00 | CYP2D6 (0.47) | CYP2D6KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL7959886 | 0.90 | KDM4E (0.47) | CYP2D6KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL7976128 | 0.90 | KDM4E (0.47) | CYP2D6KMT2ACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308519-B1 | Process for improving optical purity of azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2006-04-19 | — | — | EP | disclosed |
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-1308519-A1 | Process for improving optical purity of azetidine-2-carboxylic acid | Sumitomo Chemical Company, Limited (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-0855446-B1 | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6410279-B1 | GENERATING PREFERENTIAL COMPOUND IN SOLUTION; OBTAIN N-SUBSTITUTED AZETIDINE-2-CARBOXYLIC ACID ESTER, INCUBATE WITH PREFERENTIAL ENZYME, RECOVER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6162621-A | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0855446-A2 | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |