Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686023 | 0.78 | GRM2 (0.43) | GRM2TLR8SLC9A1ALDH1A1GPR139 | |
| SCHEMBL19911456 | 0.76 | GRM2 (0.70) | GRM2TLR8SLC9A1ALDH1A1LMNA | |
| SCHEMBL30643299 | 0.73 | GRM2 (0.48) | GRM2TLR8SLC9A1 | |
| SCHEMBL19911457 | 0.72 | GRM2 (0.69) | GRM2TLR8SLC9A1ALDH1A1 | |
| SCHEMBL17828279 | 0.72 | GRM2 (0.67) | GRM2TLR8SLC9A1 | |
| SCHEMBL5162824 | 0.71 | GRM2 (0.41) | GRM2TLR8SLC9A1KDM4EHPGD | |
| SCHEMBL12971549 | 0.70 | RPS6KA3 (0.50) | GRM2SLC9A1KDM4EALDH1A1 | |
| SCHEMBL4233106 | 0.69 | GRM2 (0.49) | GRM2SLC9A1 | |
| SCHEMBL17728249 | 0.68 | GRM2 (0.46) | GRM2TLR8SLC9A1 | |
| SCHEMBL6241554 | 0.68 | GRM2 (0.46) | GRM2TLR8SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625240-A1 | QUENCHING FLUID COMPOSITION | A. & A. FRATELLI PARODI S.R.L. (IT) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099450-A1 | QUENCHING FLUID COMPOSITION | A. & A. FRATELLI PARODI S.R.L. (IT) | 2004-11-18 | — | — | WO | disclosed |