Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.75 |
| ▸ | CNR2 | P34972 | 14/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233761 | 0.92 | CNR1 (0.85) | CNR1CNR2KCNH2 | |
| SCHEMBL1315332 | 0.92 | CNR1 (0.86) | CNR1CNR2KCNH2 | |
| Otenabant SCHEMBL1622757 | 0.86 | CNR1 (1.00) | CNR1CNR2KCNH2 | |
| SCHEMBL5236729 | 0.85 | CNR1 (0.71) | CNR1CNR2KCNH2 | |
| Otenabant SCHEMBL3932007 | 0.85 | CNR1 (0.98) | CNR1CNR2KCNH2 | |
| SCHEMBL5240651 | 0.85 | CNR1 (0.84) | CNR1CNR2KCNH2 | |
| SCHEMBL8012474 | 0.83 | CNR1 (0.85) | CNR1CNR2KCNH2 | |
| SCHEMBL5240298 | 0.82 | CNR1 (0.69) | CNR1CNR2KCNH2 | |
| SCHEMBL5238726 | 0.82 | CNR1 (0.64) | CNR1CNR2KCNH2 | |
| SCHEMBL5238605 | 0.81 | CNR1 (0.79) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624895-A2 | A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF NICOTINE ADDICTION IN A MAMMAL | Pfizer Products Inc. (US) | 2006-02-15 | — | — | EP | claimed |
| WO-2004098580-A2 | A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF NICOTINE ADDICTION IN A MAMMAL | PFIZER PRODUCTS INC. (US) | 2004-11-18 | — | — | WO | claimed |