Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633763 | 1.00 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL5686068 | 1.00 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL5659658 | 0.91 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL5632886 | 0.90 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL5635448 | 0.89 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL5633517 | 0.89 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL5634472 | 0.88 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5635873 | 0.86 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL5685747 | 0.84 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL5685734 | 0.84 | KCNH2 (0.53) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006526000-A | — | — | 2006-11-16 | — | — | JP | claimed |
| EP-1633343-A1 | 3-AMINOMETHYL-PYRROLIDINES AS N-TYPE CALCIUM CHANNEL BLOCKERS | Neuromed Technologies, Inc. (CA) | 2006-03-15 | — | — | EP | claimed |
| WO-2004105750-A1 | 3-AMINOMETHYL-PYRROLIDINES AS N-TYPE CALCIUM CHANNEL BLOCKERS | NEUROMED TECHNOLOGIES, INC. (CA) | 2004-12-09 | — | — | WO | claimed |