SCHEMBL5686558

SCHEMBL5686558

N[C@@H](C=O)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL469068 1.00
SCHEMBL8536 1.00
Hydrochloric Acid SCHEMBL30708964 0.97 SLC22A6 (0.39)
Hydrochloric Acid SCHEMBL29274064 0.97 SLC22A6 (0.39)
SCHEMBL29045971 0.97
SCHEMBL7397717 0.78
SCHEMBL8991588 0.78
SCHEMBL10519890 0.78
SCHEMBL17234507 0.76
SCHEMBL7416325 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120398730-A Fluobenil preparation method of examination 上海贝美医药科技有限公司 2025-08-01 CN disclosed
US-9434610-B2 HPMA—docetaxel conjugates and uses therefore REXAHN PHARMACEUTICALS, INC. (US) 2016-09-06 US disclosed
WO-2015034920-A2 GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR COMPOSITIONS SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2015-03-12 WO disclosed
US-8357638-B2 Oligonucleotide library encoding randomised peptides ASTON UNIVERSITY (GB) 2013-01-22 US disclosed
US-8299212-B2 TDF-related compounds and analogs thereof, analogs and bioactive fragments THRASOS THERAPEUTICS, INC. (US) 2012-10-30 US disclosed
US-20100099644-A1 HPMA - DOCETAXEL OR GEMCITABINE CONJUGATES AND USES THEREFORE REXAHN PHARMACEUTICALS, INC. 2010-04-22 US disclosed
US-20100081786-A1 Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-04-01 US disclosed
US-20090264313-A1 Oligonucleotide library encoding randomised peptides ASTON UNIVERSITY (GB) 2009-10-22 US disclosed
US-20070280939-A1 Prostatic Acid Phosphatase Antigens NOTTINGHAM TRENT UNIVERSITY, THE (GB) 2007-12-06 US disclosed
US-20070243562-A1 Lectins for Analyzing Sugar Chains and Method of Using the Same SUMMIT GLYCORESEARCH CORPORATION (JP) 2007-10-18 US disclosed
EP-0979241-B1 (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA IVAX DRUG RES INST LTD (HU) 2006-03-01 EP disclosed
US-6593300-B1 Inhibitors of the interleukin-1 beta converting enzyme GYOGYSZERKUTATO INTEZET KFT. (HU) 2003-07-15 US disclosed
EP-0979241-A1 (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA GYOGYSZERKUTATO INTEZET KFT. (HU) 2000-02-16 EP disclosed
WO-1998049189-A1 (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA Gyógyszerkutató Intézet Kft. (HU) 1998-11-05 WO disclosed