Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 10/20 | 0.51 |
| ▸ | CNR2 | P34972 | 10/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5687962 | 0.98 | TSHR (0.54) | TSHRCASP1CNR1CNR2PDE10A | |
| SCHEMBL5687984 | 0.89 | TSHR (0.46) | TSHRCASP1CNR1CNR2PDE10A | |
| Hydrochloric Acid SCHEMBL5688141 | 0.88 | TSHR (0.44) | TSHRCASP1CNR1CNR2PDE10A | |
| SCHEMBL5684857 | 0.85 | TSHR (0.54) | TSHRCASP1CNR1CNR2PDE10A | |
| SCHEMBL6575760 | 0.85 | PDE10A (0.59) | TSHRCASP1CNR1CNR2PDE10A | |
| SCHEMBL5684819 | 0.84 | CNR2 (0.54) | TSHRCASP1CNR1CNR2PDE10A | |
| SCHEMBL5687736 | 0.83 | TSHR (0.55) | TSHRCASP1CNR1CNR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5685645 | 0.83 | TSHR (0.52) | TSHRCASP1CNR1CNR2PDE10A | |
| Hydrochloric Acid SCHEMBL6776909 | 0.83 | PDE10A (0.57) | TSHRCASP1CNR1CNR2PDE10A | |
| Hydrochloric Acid SCHEMBL5688030 | 0.83 | CNR2 (0.53) | TSHRCASP1CNR1CNR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7077872-B2 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AG (DE) | 2006-07-18 | — | — | US | disclosed |
| EP-1418879-B1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | KRT18, S100P, ALDH7A1 | TSHR 2675/4885CASP1 2849/4885CNR1 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.