SCHEMBL568865

SCHEMBL568865

O=CC1CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28152365 1.00
SCHEMBL21757018 1.00
SCHEMBL8879058 0.75
SCHEMBL26689101 0.73
SCHEMBL1766351 0.73
SCHEMBL24850193 0.69
SCHEMBL4650477 0.69
SCHEMBL7547944 0.69
SCHEMBL3995563 0.67
SCHEMBL1305278 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116457355-A 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds 第一生物治疗股份有限公司 2023-07-18 CN claimed
CN-115537783-A Preparation process of metal surface laser strengthening coating 苏州酷咔智能科技有限公司 2022-12-30 CN claimed
US-9969716-B2 Indole derivatives as modulators of methyl modifying enzymes, compositions and uses thereof CONSTELLATION PHARMACEUTICALS, INC. (US) 2018-05-15 US claimed
CN-104583217-B Substituted thiophene-fused and furan-fused oxazolopyrimidine-5- (6H) -one compounds 达特神经科学(开曼)有限公司 2017-11-17 CN claimed
US-20160185757-A1 INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. (US) 2016-06-30 US claimed
EP-3033334-A1 INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF Constellation Pharmaceuticals, Inc. (US) 2016-06-22 EP claimed
CN-104583217-A Substituted thiophene-fused and furan-fused oxazolopyrimidine-5- (6H) -one compounds DART NEUROSCIENCE CAYMAN LTD 2015-04-29 CN claimed
WO-2015023915-A1 INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. (US) 2015-02-19 WO claimed
EP-4745126-A1 PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS Syngenta Crop Protection AG (CH) 2026-05-20 EP disclosed
EP-4482583-B1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-04-01 EP disclosed
US-20260055117-A1 SUBSTITUTED PYRIDONE GPR84 ANTAGONISTS AND USES THEREOF LIMINAL BIOSCIENCES LTD (GB) 2026-02-26 US disclosed
WO-2025137605-A1 COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR C4 THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
WO-2025133989-A1 SMYD MODULATORS AND USES THEREOF ALT-BIO PTE. LTD. (SG) 2025-06-26 WO disclosed
EP-4565590-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Kumquat Biosciences Inc. (US) 2025-06-11 EP disclosed
CN-1041730-C Process for preparing hydrogenated pyridine derivatives SANKYO CO (JP) 1999-01-20 CN disclosed
EP-0542411-B1 TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION SANKYO CO (JP) 1998-08-12 EP disclosed
US-5436242-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation SANKYO COMPANY, LIMITED (JP) 1995-07-25 US disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 US disclosed
CN-1074446-A Hydroxypyridine Derivatives SANKYO CO (JP) 1993-07-21 CN disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed