Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 11/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18770487 | 0.87 | CYP17A1 (0.63) | CYP17A1CYP3A4 | |
| SCHEMBL5690534 | 0.87 | CYP17A1 (0.60) | CYP17A1CYP3A4 | |
| SCHEMBL5688702 | 0.83 | CYP17A1 (0.53) | CYP17A1CYP3A4 | |
| SCHEMBL5688302 | 0.81 | CYP17A1 (0.46) | CYP17A1CYP3A4HTR1AHTR7CNR1 | |
| SCHEMBL5688560 | 0.81 | CYP3A4 (0.51) | CYP17A1CYP3A4AXL | |
| SCHEMBL5688934 | 0.81 | CYP17A1 (0.52) | CYP17A1CYP3A4 | |
| SCHEMBL5688356 | 0.81 | CYP17A1 (0.50) | CYP17A1CYP3A4 | |
| SCHEMBL5691318 | 0.80 | CYP17A1 (0.58) | CYP17A1CYP3A4 | |
| SCHEMBL5691340 | 0.80 | CYP17A1 (0.63) | CYP17A1CYP3A4CNR1 | |
| SCHEMBL5688515 | 0.80 | CYP17A1 (0.63) | CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |