Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 19/20 | 0.66 |
| ▸ | CCR3 | P51677 | 19/20 | 0.66 |
| ▸ | STS | P08842 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418989 | 1.00 | HRH1 (0.66) | HRH1CCR3STSKCNH2 | |
| SCHEMBL5691269 | 0.92 | HRH1 (0.78) | HRH1CCR3KCNH2 | |
| SCHEMBL5414635 | 0.92 | HRH1 (0.78) | HRH1CCR3KCNH2 | |
| SCHEMBL5689449 | 0.90 | HRH1 (0.65) | HRH1CCR3KCNH2 | |
| SCHEMBL5403836 | 0.90 | HRH1 (0.65) | HRH1CCR3KCNH2 | |
| SCHEMBL5409678 | 0.89 | HRH1 (0.84) | HRH1CCR3KCNH2 | |
| SCHEMBL5406460 | 0.86 | HRH1 (0.78) | HRH1CCR3KCNH2 | |
| SCHEMBL5689132 | 0.86 | HRH1 (0.78) | HRH1CCR3KCNH2 | |
| SCHEMBL5407325 | 0.86 | HRH1 (0.62) | HRH1CCR3KCNH2 | |
| SCHEMBL5689552 | 0.86 | HRH1 (0.62) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404667-B1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2006-03-08 | — | — | EP | claimed |