SCHEMBL5689404

SCHEMBL5689404

O=C(c1ccc(O)cc1)c1ccc(O)cc1O.O=C(c1ccccc1)c1ccc(O)c(O)c1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.76
KMT2A Q03164 6/20 0.76
USP2 O75604 1/20 0.76
GAA P10253 1/20 0.76
KEAP1 Q14145 1/20 0.76
NFE2L2 Q16236 1/20 0.76
LIG1 P18858 1/20 0.56
HDAC1 Q13547 1/20 0.54
ALDH1A1 P00352 6/20 0.54
MAPT P10636 6/20 0.54
HPGD P15428 5/20 0.54
LMNA P02545 3/20 0.54
MAPK1 P28482 3/20 0.54
NPC1 O15118 2/20 0.54
CYP1A2 P05177 1/20 0.54
PGR P06401 1/20 0.54
CYP2D6 P10635 1/20 0.54
SLC6A2 P23975 1/20 0.54
PDE4A P27815 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8861471 0.92 MEN1 (0.61) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL8658495 0.90 MEN1 (0.59) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL9857374 0.89 MEN1 (0.89) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL2053270 0.88 HDAC1 (0.58) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL6568215 0.88 HDAC1 (0.58) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL29351647 0.87 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL39681 0.87 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL30201813 0.87 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL28179616 0.87 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL28108552 0.87 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1400351-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-04-12 EP disclosed
EP-1287984-B1 Lithographic printing plate precursor sensitive to infrared laser radiation FUJI PHOTO FILM CO LTD (JP) 2006-04-12 EP disclosed
US-6949326-B2 Wear resistance; heat sensitive elements FUJI PHOTO FILM CO., LTD. (JP) 2005-09-27 US disclosed
EP-1400351-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-03-24 EP disclosed
US-20030118942-A1 Wear resistance; heat sensitive elements FUJI PHOTO FILM CO., LTD. 2003-06-26 US disclosed
EP-1287984-A1 Lithographic printing plate precursor sensitive to infrared laser radiation FUJI PHOTO FILM CO., LTD. (JP) 2003-03-05 EP disclosed
EP-0589309-A1 Positive-working presensitized plate for use in making lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 1994-03-30 EP disclosed