Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848564 | 0.98 | IDO1 (0.57) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL5689454 | 0.95 | IDO1 (0.55) | CHRM2CHRM1IDO1TAAR1CA1 | |
| Hydrochloric Acid SCHEMBL2493335 | 0.95 | IDO1 (0.59) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL11197258 | 0.89 | IDO1 (0.53) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL5158268 | 0.88 | ABCB1 (0.51) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL5689625 | 0.85 | IDO1 (0.50) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL7765798 | 0.84 | IDO1 (0.48) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL27808126 | 0.82 | IDO1 (0.55) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL3296809 | 0.78 | IDO1 (0.61) | CHRM2CHRM1IDO1TAAR1CA1 | |
| SCHEMBL28858018 | 0.78 | TAAR1 (0.75) | CHRM2CHRM1IDO1TAAR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1671976-B1 | Process for the preparation of phosphorus-containing compounds and their intermediates | STANFORD RES INST INT (US) | 2014-12-03 | — | — | EP | disclosed |
| US-7067701-B2 | Preparation of phosphorus-containing compounds useful in the preparation of biphosphine ligands | SRI INTERNATIONAL (US) | 2006-06-27 | — | — | US | disclosed |
| EP-1671976-A1 | Process for the preparation of phosphorus-containing compounds and their intermediates | Sri International (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1102771-B1 | PREPARATION OF ORGANOLITHIUM AND ORGANOPHOSPHORUS DERIVATIVES | STANFORD RES INST INT (US) | 2006-05-03 | — | — | EP | disclosed |
| US-20040147785-A1 | Preparation of phosphorus-containing compounds useful in the preparation of biphosphine ligands | VAN GINKEL ROELOF (NL) | 2004-07-29 | — | — | US | disclosed |
| US-6720442-B2 | REACTION LITHIUM PHOSPHINE COMPOUND WITH DIHALPHOSPHINE COMPOUND | SRI INTERNATIONAL | 2004-04-13 | — | — | US | disclosed |
| US-20030109754-A1 | Preparation of phosphorus-containing compounds useful in the preparation of biphosphine ligands | VAN GINKEL ROELOF (NL) | 2003-06-12 | — | — | US | disclosed |
| US-6548708-B1 | Reacting phosphineamine, oxyphosphine or thiophosphine with organic halide; forming polymerization catalyst complexes to make carbon monoxide-A-olefin copolymers | SRI INTERNATIONAL | 2003-04-15 | — | — | US | disclosed |