Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690183 | 1.00 | BCHE (0.50) | BCHEGRIN2BMRGPRX4LTA4HEPHX2 | |
| SCHEMBL5691626 | 0.86 | BCHE (0.49) | BCHEGRIN2BMRGPRX4LTA4HEPHX2 | |
| SCHEMBL5691624 | 0.86 | BCHE (0.49) | BCHEGRIN2BMRGPRX4LTA4HEPHX2 | |
| SCHEMBL4689458 | 0.86 | BCHE (0.55) | BCHEGRIN2BLTA4HEPHX2ALOX5 | |
| SCHEMBL5690254 | 0.86 | GRIN2B (0.53) | GRIN2BSPHK1 | |
| SCHEMBL5690258 | 0.86 | GRIN2B (0.53) | GRIN2BSPHK1 | |
| SCHEMBL5690208 | 0.81 | MRGPRX4 (0.50) | BCHEMRGPRX4LTA4HEPHX2ALOX5 | |
| SCHEMBL5690205 | 0.81 | MRGPRX4 (0.50) | BCHEMRGPRX4LTA4HEPHX2ALOX5 | |
| SCHEMBL7072272 | 0.81 | GRIN2B (0.50) | GRIN2BSPHK1 | |
| SCHEMBL7072271 | 0.81 | GRIN2B (0.50) | GRIN2BSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0982026-B1 | Use of aryl-cyclohexylamine derivatives in the manufacture of NMDA receptor blockers | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | EP | disclosed |
| US-6184236-B1 | Method of treating a neurodegenerative disease by administering an aryl-cyclohexylamine derivative | HOFFMANN-LA ROCHE INC. | 2001-02-06 | — | — | US | disclosed |
| EP-0982026-A2 | Use of aryl-cyclohexylamine derivatives in the manufacture of NMDA receptor blockers | F. HOFFMANN-LA ROCHE AG (CH) | 2000-03-01 | — | — | EP | disclosed |