Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117318 | 1.00 | CYP1A2 (0.57) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A | |
| SCHEMBL29399169 | 1.00 | CYP1A2 (0.57) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A | |
| SCHEMBL19182788 | 0.87 | CYP1A2 (0.47) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A | |
| SCHEMBL8617798 | 0.85 | CYP1A2 (0.58) | CYP1A2CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL7247476 | 0.85 | CYP1A2 (0.54) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A | |
| SCHEMBL14478292 | 0.85 | CYP1A2 (0.54) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A | |
| SCHEMBL4841335 | 0.85 | CYP1A2 (0.54) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A | |
| SCHEMBL14478261 | 0.85 | CYP1A2 (0.54) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A | |
| SCHEMBL4213801 | 0.82 | CYP1A2 (0.55) | CYP1A2CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL19407426 | 0.82 | CYP1A2 (0.51) | CYP1A2ALOX5APCYSLTR1CYSLTR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654197-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | Degussa AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016823-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | DEGUSSA AG (DE) | 2005-02-24 | — | — | WO | disclosed |