SCHEMBL5690833

SCHEMBL5690833

COC(=O)C1CCCCC1OC

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM3 P20309 1/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10267553 0.96 CHRM2 (0.46) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL26999198 0.96 CHRM2 (0.46) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL2691313 0.96 CHRM2 (0.46) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL15384702 0.85 SLC6A2 (0.41) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL13595131 0.84 CHRM2 (0.48) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL11514730 0.84 CHRM2 (0.48) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL8058857 0.84 CHRM2 (0.48) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL272354 0.84 CHRM2 (0.48) CHRM2CHRM4CHRM3SLC6A2SLC6A4
SCHEMBL28008749 0.82 EPHX1 (0.37) SLC6A2SLC6A4KDM4EALDH1A1MAPT
SCHEMBL28008748 0.82 EPHX1 (0.37) SLC6A2SLC6A4KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718602-B2 EGFR inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2023-08-08 US disclosed
EP-1675864-B1 PLATINUM COMPLEXES FOR THE TREATMENT OF TUMORS UNIV SOUTH FLORIDA (US) 2009-12-30 EP disclosed
CN-1882880-A Aqueous resist composition SHOWA DENKO KK (JP) 2006-12-20 CN disclosed
CN-1813221-A Resist composition SHOWA DENKO KK (JP) 2006-08-02 CN disclosed
US-20060154173-A1 Resist composition SHOWA DENKO K.K. (JP) 2006-07-13 US disclosed
EP-1644777-A2 RESIST COMPOSITION Showa Denko K.K. (JP) 2006-04-12 EP disclosed
WO-2005047978-A1 AQUEOUS RESIST COMPOSITION SHOWA DENKO K.K. (JP) 2005-05-26 WO disclosed
WO-2005003859-A2 RESIST COMPOSITION SHOWA DENKO K.K. (JP) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718602-B2 EGFR inhibitors EGFR, ERBB2, ERBB3 CHRM2 4881/4885CHRM4 4880/4885CHRM3 4870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.