Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL5080442 | 0.89 | CSNK2A1 (0.52) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 | |
| SCHEMBL107259 | 0.88 | CSNK2A1 (0.59) | NFE2L2CSNK2A1KDM4EHSD11B1RXRB | |
| SCHEMBL30679777 | 0.88 | CSNK2A1 (0.59) | NFE2L2CSNK2A1KDM4EHSD11B1RXRB | |
| Bromide SCHEMBL6113400 | 0.86 | CSNK2A1 (0.57) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 | |
| SCHEMBL6915319 | 0.86 | CSNK2A1 (0.57) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 | |
| SCHEMBL6912721 | 0.86 | CSNK2A1 (0.57) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 | |
| SCHEMBL6915656 | 0.86 | CSNK2A1 (0.57) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 | |
| SCHEMBL6916723 | 0.86 | CSNK2A1 (0.57) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 | |
| SCHEMBL6908325 | 0.86 | CSNK2A1 (0.57) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 | |
| Charcoal, Activated SCHEMBL7747676 | 0.86 | CSNK2A1 (0.57) | NFE2L2CSNK2A1KDM4EHSD11B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | disclosed |