SCHEMBL5692575

SCHEMBL5692575

CCCCCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 1/20 0.46
DNM1 Q05193 2/20 0.46
EPHX1 P07099 1/20 0.46
OPRM1 P35372 1/20 0.43
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH4 P08319 1/20 0.43
ADH7 P40394 1/20 0.43
GPR84 Q9NQS5 3/20 0.41
FDPS P14324 3/20 0.41
SPHK1 Q9NYA1 1/20 0.41
FFAR1 O14842 1/20 0.41
ZDHHC7 Q9NXF8 1/20 0.40
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9468275 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL10565724 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL8010945 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL11701212 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL11681882 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL20054095 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL12479965 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL12479364 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL13851797 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1
SCHEMBL11701657 1.00 TSHR (0.47) TSHRTHRBLMNADNM1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1240170-B1 CARBENIUM CATIONIC COMPLEXES SUITABLE FOR POLYMERIZATION CATALYSTS EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
US-6838411-B2 Combining under polymerization conditions olefins with the product of combining an organometallic catalyst compound and a cocatalyst complex comprising a trialkylsilyl-substituted compound EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-04 US disclosed
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-6475946-B1 Olefin polymerization catalysis with aryl substituted carbenium cationic complexes EXXONMOBIL CHEMICAL PATENTS INC. 2002-11-05 US disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
US-20020132728-A1 Olefin polymerization catalysis with aryl substituted carbenium cationic complexes RIX FRANCIS C (US) 2002-09-19 US disclosed
EP-1240170-A1 CARBENIUM CATIONIC COMPLEXES SUITABLE FOR POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2002-09-18 EP disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed
WO-2001030785-A1 CARBENIUM CATIONIC COMPLEXES SUITABLE FOR POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-03 WO disclosed