Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057810 | 0.94 | AR (0.55) | ARPGRS1PR1 | |
| SCHEMBL3059975 | 0.87 | AR (0.54) | ARPGR | |
| SCHEMBL3054642 | 0.81 | AR (0.59) | ARPGR | |
| SCHEMBL5175526 | 0.80 | AR (0.48) | ARPGR | |
| SCHEMBL3051139 | 0.79 | AR (0.56) | ARPGR | |
| SCHEMBL13326442 | 0.77 | AR (0.53) | ARPGRS1PR1 | |
| SCHEMBL3047904 | 0.77 | AR (0.60) | ARPGR | |
| SCHEMBL1380477 | 0.77 | AR (0.51) | ARPGR | |
| SCHEMBL3289697 | 0.77 | AR (0.55) | ARPGRS1PR1 | |
| SCHEMBL4901837 | 0.76 | AR (0.61) | ARPGRS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654221-A2 | ANILINE DERIVATIVED ANDROGEN-, GLUCOCORTICOID-, MINERALCORTICOID- AND PROGESTERONE- RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005000795-A2 | ANILINE DERIVATIVED ANDROGEN-, GLUCOCORTICOID-, MINERALCORTICOID- AND PROGESTERONE- RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-06 | — | — | WO | disclosed |