Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 11/20 | 0.48 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12400687 | 0.89 | CHRM4 (0.50) | CHRM4CALCRLRAMP1CTSSBRD4 | |
| SCHEMBL4718740 | 0.88 | CALCRL (0.44) | CHRM4CALCRLRAMP1 | |
| SCHEMBL2872824 | 0.85 | BRD4 (0.56) | CHRM4CALCRLRAMP1CTSSBRD4 | |
| SCHEMBL13313600 | 0.84 | BRD4 (0.57) | CHRM4CALCRLRAMP1CTSSBRD4 | |
| SCHEMBL13078005 | 0.82 | BRD4 (0.53) | CHRM4CALCRLRAMP1CTSSBRD4 | |
| SCHEMBL5695088 | 0.82 | CALCRL (0.49) | CHRM4CALCRLRAMP1CTSSBRD4 | |
| SCHEMBL3237433 | 0.81 | CHRM4 (0.57) | CHRM4CALCRLRAMP1 | |
| SCHEMBL9046543 | 0.80 | CHRM4 (0.70) | CHRM4CALCRLRAMP1CTSS | |
| SCHEMBL2100919 | 0.80 | BRD4 (0.50) | CHRM4CALCRLRAMP1CTSSBRD4 | |
| SCHEMBL31184539 | 0.80 | BRD4 (0.50) | CHRM4CALCRLRAMP1CTSSBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658051-A1 | MICROPARTICLES COMPRISING THE CGRP ANTAGONIST 1-¬N2 -¬ 3,5-DIBROMO- N-¬¬4-(3,4-DIHYDRO-2(1H)-OXOQUINAZOLIN-3-YL)-1-PIPERIDINYL|CARBONYL|-D-TYROSYL|-L-LYSYL|-4-(4-PYRIDINYL)-PIPERAZINE METHOD FOR PRODUCTION AND USE THEREOF AS INHALATION POWDER | Boehringer Ingelheim International GmbH (DE) | 2006-05-24 | — | — | EP | disclosed |