Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.57 |
| ▸ | NT5E | P21589 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695111 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3NT5EADORA2BADORA1 | |
| SCHEMBL7777271 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3NT5EADORA2BADORA1 | |
| SCHEMBL5694989 | 0.93 | ADORA2A (1.00) | ADORA2AADORA3NT5EADORA2BADORA1 | |
| SCHEMBL5695114 | 0.92 | ADORA2A (0.98) | ADORA2AADORA3NT5EADORA2BADORA1 | |
| SCHEMBL5694978 | 0.91 | ADORA2A (0.84) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5695146 | 0.90 | ADORA2A (0.81) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5695183 | 0.89 | ADORA2A (0.81) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5694943 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7777415 | 0.89 | ADORA2A (0.80) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6916173 | 0.87 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121372-B1 | ADENINE DERIVATIVES | PFIZER LTD (GB) | 2006-06-28 | — | — | EP | disclosed |